Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | OGA | O60502 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559247 | 0.87 | HRH3 (0.55) | HRH3L3MBTL1DPP4SMN1; SMN2OGA | |
| SCHEMBL13634292 | 0.86 | HRH3 (0.52) | HRH3L3MBTL1DPP4SMN1; SMN2OGA | |
| SCHEMBL10136842 | 0.81 | HRH3 (0.49) | HRH3L3MBTL1DPP4SMN1; SMN2OGA | |
| SCHEMBL13634185 | 0.81 | HRH3 (0.50) | HRH3L3MBTL1DPP4SMN1; SMN2OGA | |
| SCHEMBL13634365 | 0.81 | HRH3 (0.47) | HRH3L3MBTL1DPP4SMN1; SMN2OGA | |
| SCHEMBL13634296 | 0.80 | HRH3 (0.49) | HRH3L3MBTL1DPP4SMN1; SMN2OGA | |
| SCHEMBL12988798 | 0.77 | HRH3 (0.52) | HRH3L3MBTL1DPP4SMN1; SMN2OGA | |
| SCHEMBL3511935 | 0.77 | L3MBTL1 (0.54) | HRH3L3MBTL1DPP4SMN1; SMN2OGA | |
| SCHEMBL4472290 | 0.77 | L3MBTL1 (0.54) | HRH3L3MBTL1DPP4SMN1; SMN2OGA | |
| SCHEMBL458365 | 0.76 | HRH3 (0.48) | HRH3L3MBTL1DPP4SMN1; SMN2OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |