Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888540 | 0.85 | OGA (0.48) | HRH3OGARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3435877 | 0.83 | HRH3 (0.52) | PTGER1HRH3OGARAB9ASMN1; SMN2 | |
| SCHEMBL13162769 | 0.81 | HRH3 (0.47) | PTGER1HRH3OGARAB9ASMN1; SMN2 | |
| SCHEMBL13634346 | 0.80 | HRH3 (0.47) | PTGER1HRH3OGARAB9ASMN1; SMN2 | |
| SCHEMBL2078959 | 0.79 | PTGER1 (0.48) | PTGER1HRH3OGARAB9ASMN1; SMN2 | |
| SCHEMBL13162807 | 0.79 | HRH3 (0.48) | PTGER1HRH3OGARAB9ASMN1; SMN2 | |
| SCHEMBL2079085 | 0.78 | HRH3 (0.54) | PTGER1HRH3OGARAB9ASMN1; SMN2 | |
| SCHEMBL13634311 | 0.78 | HRH3 (0.47) | PTGER1HRH3OGARAB9ASMN1; SMN2 | |
| SCHEMBL13162579 | 0.78 | HRH3 (0.47) | PTGER1HRH3OGARAB9ASMN1; SMN2 | |
| SCHEMBL30295682 | 0.78 | ADORA2A (0.43) | PTGER1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |