SCHEMBL13634324

SCHEMBL13634324

CCc1coc(N(C)CC2CCOCC2)n1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 17/20 0.37
PDE7B Q9NP56 1/20 0.32
HTT P42858 1/20 0.32
CCNT1 O60563 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13162341 0.77 CSF1R (0.40) CSF1RHTT
SCHEMBL13162317 0.76 CSF1R (0.37) CSF1R
SCHEMBL15888651 0.75 NLRP3 (0.38) CSF1RCCNT1
SCHEMBL13634371 0.66
SCHEMBL13634213 0.64
SCHEMBL13634286 0.64 CSF1R (0.38) CSF1R
SCHEMBL13909016 0.63 CRHR1 (0.48) CSF1R
SCHEMBL1192444 0.63 CCNT1 (0.51) CSF1RHTTCCNT1
SCHEMBL21256824 0.63 CSF1R (0.39) CSF1RHTT
SCHEMBL24085856 0.62 PIK3CD (0.40) CSF1RHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 US disclosed