Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | SLC12A5 | Q9H2X9 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3506347 | 0.83 | MAPK1 (0.42) | NOS1SMN1; SMN2SLC12A5CYP2D6KDM4E | |
| SCHEMBL13634391 | 0.80 | NOS1 (0.34) | NOS1SMN1; SMN2SLC12A5CYP2D6KDM4E | |
| SCHEMBL3556009 | 0.80 | NOS1 (0.34) | NOS1SMN1; SMN2SLC12A5CYP2D6KDM4E | |
| SCHEMBL18674691 | 0.80 | ALDH1A1 (0.35) | NOS1SMN1; SMN2SLC12A5CYP2D6KDM4E | |
| SCHEMBL232983 | 0.80 | SMN1; SMN2 (0.40) | NOS1SMN1; SMN2ADORA2ASLC12A5CYP2D6 | |
| SCHEMBL13425206 | 0.78 | KDM4E (0.40) | SMN1; SMN2SLC12A5CYP2D6KDM4ELMNA | |
| SCHEMBL11382824 | 0.76 | HTR2C (0.48) | SMN1; SMN2SLC12A5CYP2D6KDM4ELMNA | |
| SCHEMBL11495950 | 0.75 | SMN1; SMN2 (0.36) | SMN1; SMN2SLC12A5CYP2D6KDM4ELMNA | |
| SCHEMBL770846 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL11387659 | 0.74 | KMT2A (0.37) | SMN1; SMN2SLC12A5CYP2D6KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |