SCHEMBL13634343

SCHEMBL13634343

CCc1csc(N(C)CCS(C)(=O)=O)n1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.33
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18674680 0.78 MEN1 (0.41) MEN1KMT2ALMNA
SCHEMBL13163971 0.77 L3MBTL1 (0.38) MEN1KMT2A
SCHEMBL13634285 0.75 MEN1 (0.36) MEN1KMT2ALMNA
SCHEMBL18674636 0.75 MEN1 (0.39) MEN1KMT2ALMNA
SCHEMBL13999821 0.74 RAB9A (0.52) MEN1KMT2ALMNA
SCHEMBL13634299 0.74 MEN1 (0.41) MEN1KMT2ALMNA
SCHEMBL13662109 0.73 MEN1 (0.56) MEN1KMT2ALMNAADRB2ADRB1
SCHEMBL13162289 0.72
SCHEMBL13634300 0.72 MEN1 (0.37) MEN1KMT2A
SCHEMBL13634340 0.72 MEN1 (0.37) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 US disclosed