Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772170 | 0.88 | CYP2C9 (0.41) | IRAK4GPR6 | |
| SCHEMBL13634684 | 0.87 | MCHR1 (0.39) | PARP1TNK1FGFR1KITFLT3 | |
| SCHEMBL2772028 | 0.84 | OPRK1 (0.42) | MCHR1IRAK4 | |
| SCHEMBL2770731 | 0.84 | OPRK1 (0.42) | MCHR1IRAK4F10 | |
| Hydrochloric Acid SCHEMBL2770260 | 0.83 | OPRK1 (0.41) | FGFR1MCHR1IRAK4GSK3BF10 | |
| Hydrochloric Acid SCHEMBL2770518 | 0.83 | IRAK4 (0.39) | PARP1TNK1MCHR1IRAK4EGFR | |
| SCHEMBL2772498 | 0.83 | PARP1 (0.43) | PARP1TNK1MCHR1IRAK4F10 | |
| SCHEMBL2770451 | 0.82 | GPR6 (0.43) | GPR6 | |
| SCHEMBL13634541 | 0.82 | OPRK1 (0.40) | IRAK4 | |
| SCHEMBL13634642 | 0.81 | PARP1 (0.40) | PARP1TNK1MCHR1F10GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |