Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634665 | 0.92 | AXL (0.39) | KMT2ASMN1; SMN2ACACBKDM4EMAPT | |
| SCHEMBL13634716 | 0.84 | HRH3 (0.40) | KMT2ASMN1; SMN2HRH3MAPTIRAK4 | |
| SCHEMBL2772028 | 0.83 | OPRK1 (0.42) | KMT2ASMN1; SMN2IRAK4MAPK1OPRK1 | |
| SCHEMBL13634719 | 0.82 | HRH3 (0.39) | KMT2ASMN1; SMN2HRH3MAPTIRAK4 | |
| SCHEMBL13634794 | 0.81 | HRH3 (0.38) | KMT2ASMN1; SMN2HRH3MAPTLMNA | |
| SCHEMBL13634602 | 0.80 | IDH1 (0.40) | KMT2ASMN1; SMN2HRH3IRAK4LMNA | |
| SCHEMBL13638992 | 0.80 | IRAK4 (0.39) | KMT2ASMN1; SMN2HRH3IRAK4LMNA | |
| SCHEMBL13634650 | 0.79 | IRAK4 (0.50) | KMT2AIRAK4LMNAOPRK1 | |
| SCHEMBL13638817 | 0.79 | CYP2C9 (0.35) | KMT2AMEN1IRAK4OPRK1FGFR1 | |
| SCHEMBL13634639 | 0.79 | SCD (0.34) | ALDH1A1KMT2ASMN1; SMN2MEN1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |