Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.32 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634850 | 1.00 | SCD (0.34) | SCDSCD5SMN1; SMN2POLBTSHR | |
| SCHEMBL13270769 | 0.87 | ITK (0.36) | SCDSCD5PIN1NAPEPLD | |
| SCHEMBL13634767 | 0.85 | SCD (0.37) | SCDSCD5HPGDPIN1NAPEPLD | |
| SCHEMBL13634852 | 0.85 | HDAC1 (0.36) | SCDSCD5KMT2APIN1NAPEPLD | |
| SCHEMBL13634647 | 0.85 | HDAC1 (0.36) | SCDSCD5KMT2APIN1NAPEPLD | |
| SCHEMBL13634927 | 0.83 | CNR2 (0.36) | SCDSCD5HPGDPIN1NAPEPLD | |
| SCHEMBL13270650 | 0.83 | MAPT (0.39) | SCDSCD5TSHRKMT2AALDH1A1 | |
| SCHEMBL13634665 | 0.83 | AXL (0.39) | SMN1; SMN2POLBTSHRMAPK1ACACB | |
| SCHEMBL13638833 | 0.83 | GRM2 (0.39) | SCDSCD5PIN1 | |
| SCHEMBL13634877 | 0.82 | PDCD1 (0.35) | SCDSCD5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |