Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.43 |
| ▸ | GPR6 | P46095 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270419 | 0.90 | F10 (0.40) | MCHR1IRAK4F10FGFR1ACHE | |
| SCHEMBL13634779 | 0.89 | MCHR1 (0.43) | MCHR1GPR6IRAK4UTS2RACKR3 | |
| SCHEMBL13638815 | 0.89 | MCHR1 (0.43) | MCHR1GPR6IRAK4UTS2R | |
| SCHEMBL13634814 | 0.88 | MCHR1 (0.39) | MCHR1IRAK4F10UTS2RACHE | |
| SCHEMBL13270762 | 0.88 | S1PR1 (0.40) | MCHR1GPR6IRAK4F10ACHE | |
| SCHEMBL13634816 | 0.87 | MCHR1 (0.38) | MCHR1IRAK4F10ACHENPC1 | |
| SCHEMBL13634545 | 0.86 | P2RX3 (0.41) | GPR6F10 | |
| SCHEMBL13634581 | 0.86 | ACKR3 (0.42) | MCHR1IRAK4F10ACHEACKR3 | |
| SCHEMBL13634542 | 0.85 | POLB (0.44) | IRAK4KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13634792 | 0.83 | PDE10A (0.46) | GPR6IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |