Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 4/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | DNM1L | O00429 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634598 | 0.92 | HRH3 (0.42) | GPR6SCDHDAC3HDAC2S1PR1 | |
| SCHEMBL13634679 | 0.91 | IRAK4 (0.43) | GPR6SCDDNM1LCHEK1 | |
| SCHEMBL2770451 | 0.91 | GPR6 (0.43) | GPR6SCDDNM1LHDAC3HDAC2 | |
| SCHEMBL13634849 | 0.90 | GPR6 (0.41) | GPR6SCDDNM1LHDAC3HDAC2 | |
| SCHEMBL13634698 | 0.89 | MAP3K7 (0.47) | GPR6SCDHRH3FGFR1 | |
| SCHEMBL13634621 | 0.89 | GPR6 (0.39) | GPR6SCDDNM1LHDAC3HDAC2 | |
| SCHEMBL13634709 | 0.88 | GPR6 (0.46) | GPR6SCDHDAC3HDAC2 | |
| SCHEMBL13162054 | 0.88 | SCD (0.50) | GPR6SCDHDAC3HDAC2SMN1; SMN2 | |
| SCHEMBL2772305 | 0.86 | SCD (0.45) | GPR6SCDDNM1LHDAC3HDAC2 | |
| SCHEMBL13634881 | 0.84 | NPC1 (0.40) | GPR6SCDHDAC3HDAC2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |