Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GPR6 | P46095 | 4/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC5A7 | Q9GZV3 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | DNM1L | O00429 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634606 | 0.93 | IRAK4 (0.43) | IRAK4CHEK1PDE4DSCDHPGD | |
| SCHEMBL13634609 | 0.91 | GPR6 (0.41) | CHEK1SCDGPR6DNM1L | |
| SCHEMBL2772305 | 0.90 | SCD (0.45) | SCDHPGDGPR6LMNAPYGL | |
| SCHEMBL2770451 | 0.90 | GPR6 (0.43) | CHEK1SCDGPR6DNM1L | |
| SCHEMBL13634619 | 0.90 | SCN9A (0.43) | IRAK4CHEK1PDE4DSCDHPGD | |
| SCHEMBL13634849 | 0.89 | GPR6 (0.41) | CHEK1SCDGPR6DNM1L | |
| SCHEMBL13634703 | 0.89 | PDE4D (0.42) | IRAK4CHEK1PDE4DSCDHPGD | |
| SCHEMBL13634648 | 0.89 | MAP3K7 (0.51) | IRAK4CHEK1GPR6 | |
| SCHEMBL13634621 | 0.88 | GPR6 (0.39) | CHEK1SCDGPR6DNM1L | |
| SCHEMBL13634680 | 0.87 | POLB (0.42) | IRAK4CHEK1PDE4DSCDHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |