Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 5/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | DNM1L | O00429 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634881 | 0.92 | NPC1 (0.40) | GPR6SCDNPC1GAAMAPT | |
| SCHEMBL13634653 | 0.92 | HRH3 (0.41) | GPR6SCDNPC1GAAMAPT | |
| SCHEMBL2770451 | 0.91 | GPR6 (0.43) | GPR6SCDNPC1RAB9AHDAC3 | |
| SCHEMBL13634609 | 0.90 | GPR6 (0.41) | GPR6SCDNPC1RAB9AHDAC3 | |
| SCHEMBL13634679 | 0.89 | IRAK4 (0.43) | GPR6SCDCHEK1DNM1L | |
| SCHEMBL13634863 | 0.88 | MAP3K7 (0.48) | GPR6SCD | |
| SCHEMBL13634826 | 0.88 | GPR6 (0.39) | GPR6SCDNPC1GAAMAPT | |
| SCHEMBL13162054 | 0.88 | SCD (0.50) | GPR6SCDHDAC3HDAC2PIM1 | |
| SCHEMBL13634709 | 0.88 | GPR6 (0.46) | GPR6SCDHDAC3HDAC2 | |
| SCHEMBL13634882 | 0.88 | MAP3K7 (0.39) | GPR6SCDNPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |