Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770473 | 0.92 | KMT2A (0.44) | MCHR1OPRK1KMT2AMAPTTSHR | |
| SCHEMBL2772498 | 0.91 | PARP1 (0.43) | MCHR1OPRK1KMT2AMAPTTSHR | |
| SCHEMBL13634567 | 0.90 | MCHR1 (0.39) | MCHR1OPRK1KMT2AMAPTTSHR | |
| Hydrochloric Acid SCHEMBL2770260 | 0.89 | OPRK1 (0.41) | MCHR1OPRK1KMT2AMAPTTSHR | |
| SCHEMBL2772028 | 0.88 | OPRK1 (0.42) | MCHR1OPRK1KMT2APDE4BIRAK4 | |
| SCHEMBL2770731 | 0.88 | OPRK1 (0.42) | MCHR1OPRK1KMT2AMAPTTSHR | |
| SCHEMBL13634818 | 0.86 | MCHR1 (0.41) | MCHR1F10PARP1TNK1ACHE | |
| SCHEMBL13638826 | 0.86 | MCHR1 (0.40) | MCHR1OPRK1KMT2APARP1TNK1 | |
| SCHEMBL13634642 | 0.85 | PARP1 (0.40) | MCHR1F10S1PR1PARP1TNK1 | |
| SCHEMBL13638933 | 0.85 | MCHR1 (0.39) | MCHR1KMT2AF10PARP1TNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |