Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 2/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 4/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634738 | 0.96 | GRM2 (0.35) | GRM2PDCD1CD274SCDSCD5 | |
| SCHEMBL13270650 | 0.93 | MAPT (0.39) | SCDSCD5 | |
| SCHEMBL13634767 | 0.93 | SCD (0.37) | SCDSCD5CNR2PIN1PIM1 | |
| SCHEMBL13638951 | 0.92 | PDCD1 (0.40) | GRM2PDCD1CD274SCDSCD5 | |
| SCHEMBL13634927 | 0.91 | CNR2 (0.36) | SCDSCD5CNR2PIN1PIM1 | |
| SCHEMBL13634897 | 0.90 | SCD (0.36) | SCDSCD5MCHR1CNR2PIM1 | |
| SCHEMBL13634641 | 0.89 | SCD (0.34) | GRM2SCDSCD5MCHR1CNR2 | |
| SCHEMBL13634557 | 0.89 | S1PR1 (0.42) | SCDSCD5CNR2ACKR3DRD4 | |
| SCHEMBL13634749 | 0.89 | F10 (0.38) | SCDSCD5CNR2PARP1TNK1 | |
| SCHEMBL13638824 | 0.88 | KMT2A (0.39) | GRM2PDCD1CD274SCDSCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |