Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634851 | 0.96 | PDE4B (0.44) | PDE4BMCHR1FGFR1FGFR2FGFR3 | |
| SCHEMBL13634899 | 0.92 | PDE4B (0.43) | PDE4BMCHR1FGFR1FGFR2FGFR3 | |
| SCHEMBL13163172 | 0.89 | MCHR1 (0.36) | PDE4BMCHR1PARP1PIM1 | |
| SCHEMBL13634889 | 0.88 | ACHE (0.42) | F10KMT2AIRAK4S1PR1 | |
| SCHEMBL13634785 | 0.88 | MAPK1 (0.43) | F10KMT2ASMN1; SMN2IRAK4S1PR1 | |
| SCHEMBL13634740 | 0.88 | MAPT (0.41) | KDM4EF10KMT2AIRAK4S1PR1 | |
| SCHEMBL2772472 | 0.88 | KMT2A (0.49) | KDM4EF10KMT2AIRAK4 | |
| SCHEMBL13270599 | 0.87 | MAPT (0.41) | PDE4BKDM4EF10KMT2AIRAK4 | |
| SCHEMBL13634605 | 0.87 | PIM1 (0.40) | PDE4BMCHR1PIM1KMT2AIRAK4 | |
| SCHEMBL13270449 | 0.86 | IRAK4 (0.36) | PDE4BMCHR1PIM1KMT2AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |