Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 2/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638824 | 0.94 | KMT2A (0.39) | ACKR3PARP1TNK1MCHR1GRM2 | |
| SCHEMBL13634884 | 0.94 | S1PR1 (0.40) | F10DRD4 | |
| SCHEMBL13634563 | 0.92 | PDCD1 (0.37) | ACKR3PARP1TNK1GLSMCHR1 | |
| SCHEMBL13634760 | 0.90 | GLS (0.40) | GLSSCDSCD5GPR6PIN1 | |
| SCHEMBL13634887 | 0.90 | GLS (0.36) | PARP1TNK1GLSMCHR1PDCD1 | |
| SCHEMBL13634924 | 0.90 | GLS (0.39) | GLSSCDSCD5GPR6PIN1 | |
| SCHEMBL13634751 | 0.90 | GLS (0.39) | PARP1TNK1GLSSCDSCD5 | |
| SCHEMBL13634915 | 0.89 | LMNA (0.37) | PARP1TNK1GLSPDCD1CD274 | |
| SCHEMBL13638951 | 0.89 | PDCD1 (0.40) | ACKR3PARP1TNK1MCHR1GRM2 | |
| SCHEMBL13638833 | 0.88 | GRM2 (0.39) | ACKR3PARP1TNK1MCHR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |