Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 6/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634621 | 0.93 | GPR6 (0.39) | HRH3SCDGPR6CHEK1HDAC3 | |
| SCHEMBL13634736 | 0.89 | MAP3K7 (0.40) | HRH3SCDGPR6IRAK4 | |
| SCHEMBL13634598 | 0.89 | HRH3 (0.42) | HRH3SCDGPR6CHEK1HDAC3 | |
| SCHEMBL13634606 | 0.89 | IRAK4 (0.43) | HRH3SCDGPR6CHEK1HSD17B10 | |
| SCHEMBL13634653 | 0.88 | HRH3 (0.41) | HRH3SCDGPR6CHEK1HDAC3 | |
| SCHEMBL13634527 | 0.87 | HRH3 (0.41) | HRH3SCDGPR6CHEK1HDAC3 | |
| SCHEMBL13638934 | 0.86 | SCD (0.49) | HRH3SCDGPR6HDAC3HDAC2 | |
| SCHEMBL13634695 | 0.86 | GPR6 (0.43) | HRH3SCDGPR6 | |
| SCHEMBL13638935 | 0.85 | SCD (0.44) | HRH3SCDGPR6CHEK1IRAK4 | |
| SCHEMBL13634619 | 0.84 | SCN9A (0.43) | SCDGPR6CHEK1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |