Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772305 | 0.92 | SCD (0.45) | SCDCYP2C9EPHX2CYP2J2HPGD | |
| SCHEMBL13634606 | 0.92 | IRAK4 (0.43) | SCDHPGDGPR6HRH3IRAK4 | |
| SCHEMBL13638763 | 0.90 | SCD (0.42) | SCDCYP2C9EPHX2CYP2J2HPGD | |
| SCHEMBL13270708 | 0.90 | SCD (0.43) | SCDCYP2C9EPHX2CYP2J2HPGD | |
| SCHEMBL13638934 | 0.89 | SCD (0.49) | SCDHPGDGPR6HRH3LMNA | |
| SCHEMBL13638941 | 0.89 | MAP3K7 (0.43) | SCDCYP2C9EPHX2CYP2J2GPR6 | |
| SCHEMBL13638995 | 0.88 | SCD (0.43) | SCDCYP2C9EPHX2CYP2J2HPGD | |
| SCHEMBL13634598 | 0.87 | HRH3 (0.42) | SCDGPR6HRH3IRAK4SMN1; SMN2 | |
| SCHEMBL13634653 | 0.87 | HRH3 (0.41) | SCDGPR6HRH3IRAK4SMN1; SMN2 | |
| SCHEMBL13634527 | 0.86 | HRH3 (0.41) | SCDGPR6HRH3IRAK4CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |