Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 5/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634881 | 0.93 | NPC1 (0.40) | HRH3SCDMAPTNPC1GAA | |
| SCHEMBL13634849 | 0.92 | GPR6 (0.41) | SCDMAPTNPC1GAANFKB1 | |
| SCHEMBL13634606 | 0.91 | IRAK4 (0.43) | HRH3SCDMAPTGPR6CHEK1 | |
| SCHEMBL13634598 | 0.91 | HRH3 (0.42) | HRH3SCDSMN1; SMN2GPR6CHEK1 | |
| SCHEMBL13634527 | 0.89 | HRH3 (0.41) | HRH3SCDGPR6CHEK1HDAC3 | |
| SCHEMBL13634863 | 0.88 | MAP3K7 (0.48) | HRH3SCDGPR6IRAK4 | |
| SCHEMBL13634695 | 0.88 | GPR6 (0.43) | HRH3SCDGPR6 | |
| SCHEMBL13634702 | 0.88 | HRH3 (0.41) | HRH3SCDGPR6CHEK1HDAC3 | |
| SCHEMBL13638934 | 0.88 | SCD (0.49) | HRH3SCDSMN1; SMN2GPR6HDAC3 | |
| SCHEMBL13634882 | 0.88 | MAP3K7 (0.39) | SCDMAPTNPC1GAANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |