Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638913 | 0.93 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL13634775 | 0.88 | IRAK4 (0.40) | IRAK4 | |
| SCHEMBL13634720 | 0.83 | IRAK4 (0.47) | IRAK4 | |
| SCHEMBL13634614 | 0.78 | JAK2 (0.37) | IRAK4 | |
| SCHEMBL13634718 | 0.78 | IRAK4 (0.47) | IRAK4 | |
| SCHEMBL13634408 | 0.77 | GRM2 (0.43) | — | |
| SCHEMBL13634865 | 0.77 | JAK2 (0.36) | IRAK4 | |
| SCHEMBL13638816 | 0.76 | IRAK4 (0.46) | IRAK4 | |
| SCHEMBL3436664 | 0.76 | IRAK4 (0.48) | IRAK4 | |
| SCHEMBL13634799 | 0.75 | IRAK4 (0.41) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |