Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30433564 | 0.83 | MDM2 (0.39) | CHRNA7ALDH1A1TSHRMGLL | |
| SCHEMBL27367885 | 0.83 | ATR (0.40) | CHRNA7MAOB | |
| SCHEMBL2606078 | 0.83 | ATR (0.40) | CHRNA7MAOB | |
| SCHEMBL2606087 | 0.82 | CHRNB2 (0.55) | CHRNA7TSHR | |
| SCHEMBL16130585 | 0.82 | CHRNB2 (0.55) | CHRNA7TSHR | |
| SCHEMBL27829534 | 0.82 | MAOB (0.40) | CCNCCDK8DRD2CHRNA7MAOB | |
| SCHEMBL16130557 | 0.82 | CHRNB2 (0.55) | CHRNA7TSHR | |
| SCHEMBL27829535 | 0.82 | MAOB (0.40) | CCNCCDK8DRD2CHRNA7MAOB | |
| Bromide SCHEMBL5224743 | 0.81 | CHRNB2 (0.53) | CHRNA7TSHR | |
| SCHEMBL13634727 | 0.80 | SMN1; SMN2 (0.44) | DRD2CHRNA7ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |