Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
| ▸ | GPR6 | P46095 | 4/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 3/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | PAICS | P22234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634607 | 0.93 | GPR6 (0.39) | GPR6CHEK1IRAK4F10CHRM4 | |
| SCHEMBL13634781 | 0.92 | GPR6 (0.40) | GPR6CHEK1IRAK4S1PR1F10 | |
| SCHEMBL13634777 | 0.91 | P2RX3 (0.44) | GPR6PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL13634545 | 0.90 | P2RX3 (0.41) | GPR6CHEK1F10PRKAB2PRKAG1 | |
| SCHEMBL13162688 | 0.86 | P2RX3 (0.42) | CHEK1IRAK4PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL13270762 | 0.85 | S1PR1 (0.40) | GPR6IRAK4S1PR1F10 | |
| SCHEMBL13270419 | 0.79 | F10 (0.40) | IRAK4S1PR1F10 | |
| SCHEMBL13634814 | 0.78 | MCHR1 (0.39) | IRAK4S1PR1F10CYP3A4 | |
| SCHEMBL13634673 | 0.77 | PIM1 (0.43) | GPR6IRAK4PAICS | |
| SCHEMBL13634816 | 0.77 | MCHR1 (0.38) | IRAK4S1PR1F10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |