Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | GPR6 | P46095 | 8/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | PAICS | P22234 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634791 | 0.96 | PIM1 (0.39) | PIM1P2RX3GPR6IRAK4DPP4 | |
| SCHEMBL13634778 | 0.96 | PIM1 (0.39) | PIM1P2RX3GPR6IRAK4DPP4 | |
| SCHEMBL13634546 | 0.86 | GPR6 (0.40) | PIM1GPR6DPP4DPP9DPP8 | |
| SCHEMBL13634777 | 0.86 | P2RX3 (0.44) | P2RX3GPR6 | |
| SCHEMBL13634545 | 0.83 | P2RX3 (0.41) | P2RX3GPR6 | |
| SCHEMBL13634635 | 0.82 | PIM1 (0.45) | PIM1GPR6IRAK4 | |
| SCHEMBL13162688 | 0.81 | P2RX3 (0.42) | P2RX3IRAK4 | |
| SCHEMBL13634835 | 0.79 | PIM1 (0.42) | PIM1GPR6PAICS | |
| SCHEMBL13634781 | 0.79 | GPR6 (0.40) | GPR6IRAK4PAICS | |
| SCHEMBL13634798 | 0.78 | PIM1 (0.48) | PIM1GPR6IRAK4PAICS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |