Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 5/20 | 0.39 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634706 | 0.95 | GPR6 (0.37) | GPR6GLSPARP1TNK1MCHR1 | |
| SCHEMBL13634526 | 0.95 | GPR6 (0.37) | GPR6GLSPARP1TNK1MCHR1 | |
| SCHEMBL13638883 | 0.94 | MCHR1 (0.35) | GPR6PARP1TNK1MCHR1SCD | |
| SCHEMBL13634583 | 0.94 | GLS (0.39) | GPR6GLSPARP1TNK1MCHR1 | |
| SCHEMBL13634885 | 0.91 | GLS (0.41) | GPR6GLSMCHR1SCDCYP2C9 | |
| SCHEMBL13634858 | 0.91 | GPR6 (0.37) | GPR6GLSPARP1TNK1MCHR1 | |
| SCHEMBL13634700 | 0.91 | GPR6 (0.37) | GPR6GLSPARP1TNK1MCHR1 | |
| SCHEMBL13634618 | 0.91 | GPR6 (0.38) | GPR6GLSPARP1TNK1MCHR1 | |
| SCHEMBL13634876 | 0.91 | GLS (0.41) | GPR6GLSPARP1TNK1MCHR1 | |
| SCHEMBL13634898 | 0.91 | GPR6 (0.37) | GPR6PARP1TNK1MCHR1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |