Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 3/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 4/20 | 0.35 |
| ▸ | BMPR1A | P36894 | 4/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 4/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634700 | 1.00 | GPR6 (0.37) | GPR6GLSMCHR1PARP1TNK1 | |
| SCHEMBL13638881 | 0.94 | SLC2A1 (0.37) | GPR6MCHR1PARP1TNK1BMPR1B | |
| SCHEMBL13638988 | 0.94 | SLC2A1 (0.37) | GPR6MCHR1PARP1TNK1BMPR1B | |
| SCHEMBL13634832 | 0.91 | GPR6 (0.39) | GPR6GLSMCHR1PARP1TNK1 | |
| SCHEMBL13634701 | 0.91 | GPR6 (0.37) | GPR6GLSMCHR1PARP1TNK1 | |
| SCHEMBL13634642 | 0.90 | PARP1 (0.40) | GPR6GLSMCHR1PARP1TNK1 | |
| SCHEMBL13634885 | 0.90 | GLS (0.41) | GPR6GLSMCHR1HRH3SCD | |
| SCHEMBL13634618 | 0.89 | GPR6 (0.38) | GPR6GLSMCHR1PARP1TNK1 | |
| SCHEMBL13634583 | 0.89 | GLS (0.39) | GPR6GLSMCHR1PARP1TNK1 | |
| SCHEMBL13634876 | 0.89 | GLS (0.41) | GPR6GLSMCHR1PARP1TNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |