Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 9/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634506 | 0.98 | PIM1 (0.39) | PIM1IRAK4PIM3PIM2CNR1 | |
| SCHEMBL13634840 | 0.94 | PIM1 (0.37) | PIM1IRAK4PIM3PIM2CNR1 | |
| SCHEMBL13638767 | 0.93 | KDM4E (0.39) | PIM1IRAK4PIM3PIM2CNR1 | |
| SCHEMBL13638905 | 0.92 | PIM1 (0.36) | PIM1IRAK4PIM3PIM2CNR1 | |
| SCHEMBL13634796 | 0.91 | GPR6 (0.37) | PIM1IRAK4PIM3PIM2CNR1 | |
| SCHEMBL13638987 | 0.91 | PIM1 (0.35) | PIM1IRAK4PIM3PIM2CNR1 | |
| SCHEMBL13634553 | 0.90 | BCL3 (0.36) | IRAK4ALDH1A1 | |
| SCHEMBL13634745 | 0.90 | BCL3 (0.36) | IRAK4ALDH1A1 | |
| SCHEMBL13634770 | 0.87 | PIM1 (0.36) | PIM1IRAK4PIM3PIM2PRKCA | |
| SCHEMBL13634505 | 0.86 | PIM1 (0.35) | PIM1IRAK4PIM3PIM2TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |