Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 6/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | PAICS | P22234 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634504 | 0.92 | PIM1 (0.37) | PIM1IRAK4PIM2PIM3GSK3B | |
| SCHEMBL13270803 | 0.91 | HCAR2 (0.40) | IRAK4CYP2C9HCAR2GPR6 | |
| SCHEMBL13634787 | 0.91 | HCAR2 (0.40) | IRAK4CYP2C9HCAR2GPR6 | |
| SCHEMBL13634505 | 0.91 | PIM1 (0.35) | PIM1IRAK4PIM2PIM3GSK3B | |
| SCHEMBL13634622 | 0.89 | PIM1 (0.48) | PIM1IRAK4PIM2PIM3CYP2C9 | |
| SCHEMBL13634796 | 0.89 | GPR6 (0.37) | PIM1IRAK4PIM2PIM3GPR6 | |
| SCHEMBL13634506 | 0.88 | PIM1 (0.39) | PIM1IRAK4PIM2PIM3GSK3B | |
| SCHEMBL13634623 | 0.87 | PIM1 (0.44) | PIM1IRAK4GPR6 | |
| SCHEMBL13634839 | 0.87 | PIM1 (0.39) | PIM1IRAK4PIM2PIM3GSK3B | |
| SCHEMBL13634840 | 0.87 | PIM1 (0.37) | PIM1IRAK4PIM2PIM3GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |