Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL3 | P20749 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | FSHR | P23945 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634553 | 1.00 | BCL3 (0.36) | BCL3POLBIRAK4KMT2AFSHR | |
| SCHEMBL13634506 | 0.92 | PIM1 (0.39) | IRAK4ALDH1A1 | |
| SCHEMBL13634726 | 0.92 | GPR6 (0.38) | BCL3POLBIRAK4KMT2AALDH1A1 | |
| SCHEMBL13634839 | 0.90 | PIM1 (0.39) | IRAK4ALDH1A1 | |
| SCHEMBL13634787 | 0.88 | HCAR2 (0.40) | IRAK4KMT2AALDH1A1MEN1FGFR1 | |
| SCHEMBL13270803 | 0.88 | HCAR2 (0.40) | IRAK4KMT2AALDH1A1MEN1FGFR1 | |
| SCHEMBL13634890 | 0.86 | ALDH1A1 (0.37) | IRAK4KMT2AALDH1A1FGFR1LMNA | |
| SCHEMBL13634860 | 0.86 | POLB (0.43) | POLBKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL13634625 | 0.86 | MEN1 (0.40) | IRAK4KMT2AALDH1A1MEN1PKM | |
| SCHEMBL13634544 | 0.86 | MEN1 (0.40) | IRAK4KMT2AALDH1A1MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |