Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 3/20 | 0.34 |
| ▸ | FPR2 | P25090 | 3/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638906 | 0.96 | F10 (0.37) | S1PR1F10ADORA2AADORA1MAP4K1 | |
| SCHEMBL13634521 | 0.91 | JAK2 (0.35) | S1PR1F10ACKR3 | |
| SCHEMBL13634893 | 0.90 | ADORA2A (0.38) | S1PR1F10ADORA2AADORA1MAP4K1 | |
| SCHEMBL13270438 | 0.90 | ADORA2A (0.38) | S1PR1F10ADORA2AADORA1MAP4K1 | |
| SCHEMBL13634595 | 0.87 | S1PR1 (0.49) | S1PR1ACKR3 | |
| SCHEMBL13638884 | 0.83 | S1PR1 (0.47) | S1PR1ACKR3 | |
| SCHEMBL13634668 | 0.80 | F10 (0.37) | S1PR1F10 | |
| SCHEMBL13634911 | 0.77 | KMT2A (0.45) | S1PR1F10 | |
| SCHEMBL13634788 | 0.77 | S1PR1 (0.48) | S1PR1MAP4K1 | |
| SCHEMBL13634780 | 0.77 | S1PR1 (0.48) | S1PR1MAP4K1ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |