Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NAPEPLD | Q6IQ20 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772504 | 0.95 | KMT2A (0.51) | KMT2AS1PR1MAPTTSHRMEN1 | |
| SCHEMBL13634867 | 0.90 | DRD4 (0.40) | KMT2AS1PR1MAPTTSHRMEN1 | |
| SCHEMBL13634678 | 0.89 | JAK2 (0.35) | KMT2AS1PR1MAPTTSHRMEN1 | |
| SCHEMBL13634668 | 0.86 | F10 (0.37) | KMT2AS1PR1MAPTMEN1ALDH1A1 | |
| SCHEMBL13634746 | 0.86 | KMT2A (0.46) | KMT2AS1PR1MAPTTSHRMEN1 | |
| SCHEMBL13163174 | 0.85 | KMT2A (0.39) | KMT2AS1PR1MAPTTSHRMEN1 | |
| SCHEMBL13162048 | 0.85 | KMT2A (0.44) | KMT2AS1PR1MAPTTSHRMEN1 | |
| SCHEMBL13638877 | 0.85 | KMT2A (0.38) | KMT2AMAPTTSHRMEN1ALDH1A1 | |
| SCHEMBL13634595 | 0.83 | S1PR1 (0.49) | S1PR1TSHRMAPK1 | |
| SCHEMBL13634662 | 0.83 | IRAK4 (0.47) | KMT2AMAPTTSHRF10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |