Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.35 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.35 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634763 | 0.90 | F10 (0.38) | F10IRAK4GAATLR7TRPC3 | |
| SCHEMBL13163171 | 0.88 | F10 (0.36) | F10IRAK4GAATRPC3TRPC7 | |
| SCHEMBL13634911 | 0.86 | KMT2A (0.45) | F10GAAMAPTLMNAACHE | |
| SCHEMBL13634678 | 0.83 | JAK2 (0.35) | F10IRAK4GAAMAPTALDH1A1 | |
| SCHEMBL13634595 | 0.83 | S1PR1 (0.49) | S1PR1 | |
| SCHEMBL13634867 | 0.83 | DRD4 (0.40) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL13270464 | 0.83 | PTGES (0.37) | F10IRAK4GAATLR7TRPC3 | |
| SCHEMBL3436608 | 0.82 | GAA (0.43) | GAAHPGDLMNAACHEKDM4E | |
| SCHEMBL13634748 | 0.81 | S1PR1 (0.36) | F10IRAK4GAAS1PR1 | |
| SCHEMBL2772504 | 0.81 | KMT2A (0.51) | F10GAAMAPTLMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |