Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | CBLB | Q13191 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | NAPEPLD | Q6IQ20 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163174 | 0.96 | KMT2A (0.39) | DRD4CCKARCBLBGRM2KCNH2 | |
| SCHEMBL13163173 | 0.91 | GRM2 (0.37) | CCKARCBLBGRM2KCNH2S1PR1 | |
| SCHEMBL13634911 | 0.90 | KMT2A (0.45) | S1PR1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL2772504 | 0.86 | KMT2A (0.51) | S1PR1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL13634668 | 0.83 | F10 (0.37) | S1PR1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL13634678 | 0.83 | JAK2 (0.35) | GRM2S1PR1KMT2AMEN1CYP1A2 | |
| SCHEMBL13634657 | 0.82 | DRD4 (0.41) | DRD4GRM2KCNH2S1PR1KMT2A | |
| SCHEMBL13634656 | 0.82 | DRD4 (0.41) | DRD4GRM2KCNH2S1PR1KMT2A | |
| SCHEMBL13634595 | 0.81 | S1PR1 (0.49) | S1PR1SIGMAR1TSHR | |
| SCHEMBL13639001 | 0.79 | KMT2A (0.38) | DRD4CCKARCBLBGRM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |