Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28876868 | 0.88 | HPGD (0.60) | SMN1; SMN2MAPTHPGDRAB9ANPC1 | |
| SCHEMBL28322545 | 0.88 | HPGD (0.60) | SMN1; SMN2MAPTHPGDRAB9ANPC1 | |
| SCHEMBL29440964 | 0.88 | HPGD (0.60) | SMN1; SMN2MAPTHPGDRAB9ANPC1 | |
| SCHEMBL8207167 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTHPGDRAB9ANPC1 | |
| SCHEMBL29171418 | 0.85 | HPGD (0.62) | SMN1; SMN2MAPTHPGDRAB9ANPC1 | |
| SCHEMBL2743575 | 0.84 | TDP1 (0.49) | SMN1; SMN2MAPTHPGDRAB9ANPC1 | |
| SCHEMBL931524 | 0.82 | HPGD (0.52) | SMN1; SMN2HPGDRAB9ATDP1 | |
| SCHEMBL931179 | 0.81 | HPGD (0.54) | SMN1; SMN2HPGDRAB9ATDP1 | |
| SCHEMBL29171440 | 0.80 | HPGD (0.56) | MAPTHPGDRAB9ANPC1LMNA | |
| SCHEMBL13125236 | 0.80 | RAB9A (0.54) | SMN1; SMN2MAPTHPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119722-A1 | Labelled nucleotides | Illumina Cambridge Limited (GB) | 2009-11-18 | — | — | EP | disclosed |
| EP-1560838-B1 | LABELLED NUCLEOTIDES | ILLUMINA CAMBRIDGE LTD (GB) | 2009-05-13 | — | — | EP | disclosed |