Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207167 | 0.87 | SMN1; SMN2 (0.59) | TDP1L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL13635133 | 0.84 | SMN1; SMN2 (0.53) | TDP1POLBMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL931524 | 0.82 | HPGD (0.52) | TDP1L3MBTL1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL1989713 | 0.81 | KMT2A (0.62) | TDP1L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL931179 | 0.81 | HPGD (0.54) | TDP1L3MBTL1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL14706761 | 0.80 | ABCB1 (0.55) | TDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8155574 | 0.78 | L3MBTL1 (0.60) | TDP1L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL11941542 | 0.77 | GRM2 (0.49) | TDP1L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL931897 | 0.77 | KMT2A (0.69) | TDP1L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL11198075 | 0.77 | ALDH1A1 (0.64) | TDP1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595508-B2 | Nucleotide cleavable linkers and uses thereof | Singular Genomics Systems, Inc. (US) | 2026-04-07 | — | — | US | disclosed |
| US-12577271-B2 | Modified nucleotides and uses thereof | Singular Genomics Systems, Inc. (US) | 2026-03-17 | — | — | US | disclosed |
| US-20260028667-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-20250361260-A1 | NUCLEOTIDE ANALOGUES | SINGULAR GENOMICS SYSTEMS INC (US) | 2025-11-27 | — | — | US | disclosed |
| EP-4117682-B1 | MODIFIED NUCLEOTIDES AND USES THEREOF | SINGULAR GENOMICS SYSTEMS INC (US) | 2025-06-04 | — | — | EP | disclosed |
| US-12215122-B2 | Nucleotide analogues | Singular Genomics Systems, Inc. (US) | 2025-02-04 | — | — | US | disclosed |
| US-20240400602-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2024-12-05 | — | — | US | disclosed |
| US-12145960-B2 | Nucleotide analogues | Singular Genomics Systems, Inc. (US) | 2024-11-19 | — | — | US | disclosed |
| US-20240271205-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2024-08-15 | — | — | US | disclosed |
| CN-113039191-B | Nucleotide analogues | 奇异基因组学系统公司 | 2024-07-16 | — | — | CN | disclosed |
| US-20090062145-A1 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2009-03-05 | — | — | US | disclosed |
| EP-2021415-A2 | DYE COMPOUNDS AND THE USE OF THEIR LABELLED CONJUGATES | Solexa Limited (GB) | 2009-02-11 | — | — | EP | disclosed |
| US-7414116-B2 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | ILLUMINA CAMBRIDGE LIMITED (GB) | 2008-08-19 | — | — | US | disclosed |
| US-7414116-B2 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | ILLUMINA CAMBRIDGE LIMITED (GB) | 2008-08-19 | — | — | US | disclosed |
| US-7414116-B2 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | ILLUMINA CAMBRIDGE LIMITED (GB) | 2008-08-19 | — | — | US | disclosed |
| WO-2007135368-A2 | DYE COMPOUNDS AND THE USE OF THEIR LABELLED CONJUGATES | SOLEXA LIMITED (GB) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007135368-A2 | DYE COMPOUNDS AND THE USE OF THEIR LABELLED CONJUGATES | SOLEXA LIMITED (GB) | 2007-11-29 | — | — | WO | disclosed |
| US-20060160081-A1 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | ILLUMINA CAMBRIDGE LIMITED (GB) | 2006-07-20 | — | — | US | disclosed |
| EP-1560838-A1 | LABELLED NUCLEOTIDES | Solexa Limited (GB) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004018493-A1 | LABELLED NUCLEOTIDES | SOLEXA LIMITED (GB) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160081-A1 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | RNGTT, DNTT, POLQ | TDP1 536/4885L3MBTL1 1287/4885MEN1 1778/4885 |
| US-12595508-B2 | Nucleotide cleavable linkers and uses thereof | NSUN2, CCRL2, NOP2 | TDP1 1091/4885L3MBTL1 844/4885MEN1 4378/4885 |
| US-12215122-B2 | Nucleotide analogues | NUDT1, POLN, TYMP | TDP1 117/4885L3MBTL1 329/4885MEN1 2845/4885 |
| US-12577271-B2 | Modified nucleotides and uses thereof | NUDT1, NSUN2, CCRL2 | TDP1 951/4885L3MBTL1 857/4885MEN1 2476/4885 |
| US-20240271205-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | NUDT21, CPSF7, DCLRE1A | TDP1 99/4885L3MBTL1 148/4885MEN1 2454/4885 |
| US-20240400602-A1 | NUCLEOTIDE ANALOGUES | ADAR, NUDT1, NSUN2 | TDP1 98/4885L3MBTL1 370/4885MEN1 2794/4885 |
| US-20250361260-A1 | NUCLEOTIDE ANALOGUES | ADAR, NUDT1, NSUN2 | TDP1 98/4885L3MBTL1 370/4885MEN1 2794/4885 |
| US-20260028667-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | POLN, NSUN2, POLL | TDP1 56/4885L3MBTL1 251/4885MEN1 2600/4885 |
| US-12145960-B2 | Nucleotide analogues | ITPA, POLB, NUDT1 | TDP1 205/4885L3MBTL1 773/4885MEN1 2745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.