Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 7/20 | 0.40 |
| ▸ | HTR7 | P34969 | 6/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3777210 | 0.87 | HTR2B (0.46) | HTR2BHTR7SLC9A1MEN1KMT2A | |
| SCHEMBL3771711 | 0.76 | HTR2B (0.43) | HTR2BHTR7SLC9A1HTR5A | |
| SCHEMBL13011638 | 0.73 | HTR2B (0.44) | HTR2BHTR7SLC9A1HTR5A | |
| SCHEMBL13011684 | 0.73 | HTR2B (0.45) | HTR2BHTR7SLC9A1ALDH1A1NPC1 | |
| SCHEMBL13011567 | 0.72 | RAB9A (0.42) | OPRK1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL13011911 | 0.72 | NPC1 (0.46) | KLKB1KLK1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL13011775 | 0.72 | HTR2B (0.46) | HTR2BHTR7SLC9A1OPRM1OPRK1 | |
| SCHEMBL13011375 | 0.71 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1POLBHPGD | |
| SCHEMBL13011681 | 0.71 | HTR2B (0.45) | HTR2BHTR7SLC9A1HDAC1HDAC6 | |
| SCHEMBL3767125 | 0.70 | CYP19A1 (0.53) | HTR2BHTR7SLC9A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119704-A1 | ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |