Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405571 | 0.91 | VCAM1 (0.54) | VCAM1MEN1KMT2ALMNARXFP1 | |
| SCHEMBL30863327 | 0.85 | VCAM1 (0.66) | VCAM1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL2773008 | 0.83 | VCAM1 (0.54) | VCAM1MEN1KMT2ALMNARXFP1 | |
| SCHEMBL13011426 | 0.82 | VCAM1 (0.53) | VCAM1MEN1KMT2ALMNARXFP1 | |
| SCHEMBL2484847 | 0.80 | VCAM1 (0.57) | VCAM1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL13011190 | 0.80 | VCAM1 (0.51) | VCAM1MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL13011439 | 0.80 | VCAM1 (0.51) | VCAM1MEN1KMT2ALMNARXFP1 | |
| SCHEMBL3775502 | 0.80 | ERN1 (0.54) | VCAM1MEN1KMT2ALMNARXFP1 | |
| SCHEMBL11330293 | 0.80 | VCAM1 (0.56) | VCAM1LMNAALDH1A1HPGDNPSR1 | |
| SCHEMBL3781413 | 0.79 | VCAM1 (0.50) | VCAM1MEN1KMT2ALMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119704-A1 | ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |