Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635199 | 0.79 | MAPK14 (0.40) | MAPK14 | |
| SCHEMBL13602980 | 0.79 | MAPK14 (0.70) | MAPK14 | |
| SCHEMBL13635902 | 0.74 | MAPK14 (0.49) | MAPK14 | |
| SCHEMBL13635309 | 0.68 | MAPK14 (0.55) | MAPK14 | |
| SCHEMBL20873900 | 0.68 | MAPK14 (0.61) | MAPK14 | |
| SCHEMBL13602979 | 0.67 | MAPK14 (0.62) | MAPK14 | |
| SCHEMBL30336047 | 0.67 | MAPK14 (0.66) | MAPK14 | |
| SCHEMBL13602986 | 0.67 | MAPK14 (0.61) | MAPK14 | |
| SCHEMBL29437782 | 0.67 | MAPK14 (0.61) | MAPK14 | |
| SCHEMBL4379663 | 0.66 | MAPK14 (0.62) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-B1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORP (US) | 2009-11-18 | — | — | EP | disclosed |