Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4384652 | 0.81 | MAPK14 (0.60) | MAPK14 | |
| Trifluoroacetic Acid SCHEMBL3526562 | 0.78 | MAPK14 (0.44) | MAPK14 | |
| SCHEMBL13635200 | 0.75 | MAPK14 (0.45) | MAPK14 | |
| SCHEMBL13635178 | 0.75 | MAPK14 (0.56) | MAPK14 | |
| SCHEMBL13602983 | 0.74 | MAPK14 (0.65) | MAPK14 | |
| SCHEMBL30336047 | 0.74 | MAPK14 (0.66) | MAPK14 | |
| SCHEMBL13635195 | 0.74 | MAPK14 (0.42) | MAPK14 | |
| SCHEMBL6473251 | 0.72 | MAPK14 (0.77) | MAPK14 | |
| SCHEMBL13602976 | 0.72 | MAPK14 (0.68) | MAPK14 | |
| SCHEMBL13602980 | 0.72 | MAPK14 (0.70) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-B1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORP (US) | 2009-11-18 | — | — | EP | disclosed |