Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635195 | 0.79 | MAPK14 (0.42) | MAPK14 | |
| SCHEMBL4383492 | 0.77 | MAPK14 (0.68) | MAPK14 | |
| SCHEMBL13635200 | 0.75 | MAPK14 (0.45) | MAPK14 | |
| SCHEMBL13635314 | 0.71 | MAPK14 (0.49) | MAPK14 | |
| SCHEMBL3520390 | 0.71 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL4387510 | 0.70 | MAPK14 (0.67) | MAPK14 | |
| SCHEMBL4384930 | 0.70 | MAPK14 (0.61) | MAPK14 | |
| SCHEMBL13635315 | 0.69 | MAPK14 (0.45) | MAPK14 | |
| SCHEMBL4384623 | 0.69 | MAPK14 (0.64) | MAPK14 | |
| SCHEMBL13635309 | 0.68 | MAPK14 (0.55) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-B1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORP (US) | 2009-11-18 | — | — | EP | disclosed |