Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.49 |
| ▸ | GABRE | P78334 | 1/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13011205 | 1.00 | ALDH1A1 (0.51) | ALDH1A1NPSR1ATMSMN1; SMN2GABRP | |
| SCHEMBL13011202 | 1.00 | ALDH1A1 (0.51) | ALDH1A1NPSR1ATMSMN1; SMN2GABRP | |
| SCHEMBL28267709 | 0.93 | ALDH1A1 (0.51) | ALDH1A1NPSR1ATMSMN1; SMN2GABRP | |
| SCHEMBL3805093 | 0.90 | ALDH1A1 (0.43) | ALDH1A1NPSR1ATMSMN1; SMN2GABRP | |
| SCHEMBL3805090 | 0.89 | KIF11 (0.42) | ALDH1A1NPSR1ATMSMN1; SMN2GABRP | |
| SCHEMBL3767138 | 0.89 | SCARB1 (0.45) | ALDH1A1NPSR1ATMSMN1; SMN2GABRP | |
| SCHEMBL3767133 | 0.89 | SCARB1 (0.45) | ALDH1A1NPSR1ATMSMN1; SMN2GABRP | |
| SCHEMBL3779471 | 0.89 | SCARB1 (0.45) | ALDH1A1NPSR1ATMSMN1; SMN2GABRP | |
| SCHEMBL3783032 | 0.88 | SCARB1 (0.44) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13011096 | 0.88 | KIF11 (0.46) | ALDH1A1NPSR1ATMSMN1; SMN2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119704-A1 | ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |