Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635169 | 0.91 | P2RY12 (0.60) | P2RY12GAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4415315 | 0.89 | P2RY12 (0.52) | P2RY12GAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13635102 | 0.87 | P2RY12 (0.51) | P2RY12GAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13635050 | 0.86 | P2RY12 (0.48) | P2RY12GAAKDM4EALDH1A1GLA | |
| SCHEMBL13635071 | 0.86 | P2RY12 (0.55) | P2RY12GAAALDH1A1SMN1; SMN2GLA | |
| SCHEMBL4418832 | 0.84 | P2RY12 (0.54) | P2RY12GAASMN1; SMN2POLBTP53 | |
| SCHEMBL13634873 | 0.84 | P2RY12 (0.52) | P2RY12GAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13635629 | 0.84 | P2RY12 (0.52) | P2RY12GAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13635177 | 0.84 | P2RY12 (0.57) | P2RY12GAASMN1; SMN2POLBTP53 | |
| SCHEMBL13635070 | 0.84 | P2RY12 (0.52) | P2RY12GAAALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668002-B1 | 2,4-DIOXO-3-QUINAZOLINYLARYL SULFONYLUREAS | PORTOLA PHARM INC (US) | 2009-11-11 | — | — | EP | disclosed |