Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635284 | 0.91 | P2RY12 (0.49) | P2RY12KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL13635279 | 0.89 | P2RY12 (0.63) | P2RY12SMN1; SMN2POLBMAPTFBP1 | |
| SCHEMBL13635081 | 0.89 | P2RY12 (0.60) | P2RY12KMT2ASMN1; SMN2HTTMAPT | |
| SCHEMBL13635261 | 0.89 | P2RY12 (0.64) | P2RY12KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL13635166 | 0.88 | P2RY12 (0.60) | P2RY12KMT2AGAAMAPTMEN1 | |
| SCHEMBL13634932 | 0.88 | P2RY12 (0.63) | P2RY12KMT2AGAASMN1; SMN2HTT | |
| SCHEMBL13635626 | 0.88 | P2RY12 (0.58) | P2RY12KMT2ASMN1; SMN2HTTMAPT | |
| SCHEMBL13635110 | 0.88 | P2RY12 (0.66) | P2RY12KMT2AGAASMN1; SMN2HTT | |
| SCHEMBL13635064 | 0.88 | P2RY12 (0.60) | P2RY12KMT2ASMN1; SMN2HTTMAPT | |
| SCHEMBL13635624 | 0.87 | P2RY12 (0.60) | P2RY12KMT2AALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668002-B1 | 2,4-DIOXO-3-QUINAZOLINYLARYL SULFONYLUREAS | PORTOLA PHARM INC (US) | 2009-11-11 | — | — | EP | disclosed |