Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | WRN | Q14191 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841987 | 0.74 | NISCH (0.53) | ALDH1A1KDM4EHSD17B10HPGDNISCH | |
| SCHEMBL3147296 | 0.72 | GALK1 (0.54) | ALPLMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL3141969 | 0.69 | GALK1 (0.49) | ALPLMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL3147159 | 0.69 | GALK1 (0.52) | ALPLMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8993558 | 0.68 | GSK3B (0.49) | ALPLMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8993530 | 0.68 | GSK3B (0.49) | ALPLMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL3151453 | 0.68 | GSK3B (0.49) | ALPLMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL13673710 | 0.66 | CYP2C19 (0.55) | ALPLGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4294439 | 0.62 | MEN1 (1.00) | MEN1KMT2ATSHRALDH1A1GAA | |
| SCHEMBL2676672 | 0.61 | MAOA (0.59) | ALPLMEN1KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119708-A1 | TETRAHYDROQUINAZOLINE COMPOUNDS AND THEIR USE IN PREPARING MEDICAMENTS FOR TREATING AND PREVENTING VIROSIS | Beijing Molecule Science and Technology Co., Ltd. (CN) | 2009-11-18 | — | — | EP | disclosed |