Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.60 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635081 | 0.89 | P2RY12 (0.60) | P2RY12FBP1MAPTTP53RXFP1 | |
| SCHEMBL13635166 | 0.87 | P2RY12 (0.60) | P2RY12FBP1MAPTTP53RXFP1 | |
| SCHEMBL13635169 | 0.87 | P2RY12 (0.60) | P2RY12FBP1MAPTTP53HTT | |
| SCHEMBL13635110 | 0.87 | P2RY12 (0.66) | P2RY12FBP1MAPTTP53RXFP1 | |
| SCHEMBL13635279 | 0.86 | P2RY12 (0.63) | P2RY12FBP1MAPTTP53RXFP1 | |
| SCHEMBL13635168 | 0.86 | P2RY12 (0.61) | P2RY12FBP1MAPTTP53RXFP1 | |
| SCHEMBL13635065 | 0.86 | P2RY12 (0.60) | P2RY12FBP1MAPTTP53RXFP1 | |
| SCHEMBL13634806 | 0.86 | P2RY12 (0.60) | P2RY12FBP1MAPTTP53RXFP1 | |
| SCHEMBL9922564 | 0.86 | P2RY12 (0.69) | P2RY12FBP1MAPTTP53RXFP1 | |
| SCHEMBL13635621 | 0.86 | P2RY12 (0.60) | P2RY12FBP1MAPTTP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668002-B1 | 2,4-DIOXO-3-QUINAZOLINYLARYL SULFONYLUREAS | PORTOLA PHARM INC (US) | 2009-11-11 | — | — | EP | disclosed |