Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.63 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GSAP | A4D1B5 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635114 | 0.90 | P2RY12 (0.66) | P2RY12FBP1HTR3ALMNASMN1; SMN2 | |
| SCHEMBL13635169 | 0.89 | P2RY12 (0.60) | P2RY12FBP1SMN1; SMN2MAPTTP53 | |
| SCHEMBL13635081 | 0.88 | P2RY12 (0.60) | P2RY12FBP1HTR3ALMNASMN1; SMN2 | |
| SCHEMBL13635281 | 0.88 | P2RY12 (0.68) | P2RY12FBP1HTR3ALMNASMN1; SMN2 | |
| SCHEMBL13635088 | 0.88 | P2RY12 (0.66) | P2RY12FBP1HTR3ALMNASMN1; SMN2 | |
| SCHEMBL13635166 | 0.88 | P2RY12 (0.60) | P2RY12FBP1MAPTTP53RXFP1 | |
| SCHEMBL13635173 | 0.88 | P2RY12 (0.66) | P2RY12FBP1HTR3ALMNASMN1; SMN2 | |
| SCHEMBL13635061 | 0.88 | P2RY12 (0.61) | P2RY12FBP1HTR3AMAPTTP53 | |
| SCHEMBL13635110 | 0.87 | P2RY12 (0.66) | P2RY12FBP1HTR3ALMNASMN1; SMN2 | |
| SCHEMBL13635624 | 0.86 | P2RY12 (0.60) | P2RY12FBP1HTR3ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668002-B1 | 2,4-DIOXO-3-QUINAZOLINYLARYL SULFONYLUREAS | PORTOLA PHARM INC (US) | 2009-11-11 | — | — | EP | disclosed |