Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13011475 | 0.87 | PTGER4 (0.58) | CNR2KDM4EPTGER4HTR7CNR1 | |
| SCHEMBL13011460 | 0.83 | OPRK1 (0.55) | CNR2PTGER4CNR1 | |
| SCHEMBL13011761 | 0.81 | CNR2 (0.50) | CNR2KDM4EPTGER4HTR7CNR1 | |
| SCHEMBL18028057 | 0.78 | POLB (0.58) | CNR2KMT2AHTR7 | |
| SCHEMBL13011314 | 0.78 | PTGER4 (0.59) | CNR2PTGER4HTR7CNR1 | |
| SCHEMBL13635107 | 0.74 | MEN1 (0.47) | CNR2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL13011305 | 0.74 | CNR1 (0.58) | ATMCNR1 | |
| SCHEMBL10702606 | 0.73 | KDM4E (0.60) | CNR2KDM4EKMT2A | |
| SCHEMBL13011809 | 0.72 | CNR1 (0.48) | CNR2ATMPTGER4HTR7CNR1 | |
| SCHEMBL10701582 | 0.72 | KDM4E (0.62) | CNR2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119704-A1 | ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |