Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13011247 | 0.88 | KDM4E (0.57) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL13011160 | 0.86 | SCARB1 (0.50) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL13011658 | 0.83 | POLB (0.42) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL13635121 | 0.78 | PTGER4 (0.60) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL13635681 | 0.74 | CNR2 (0.54) | MEN1KMT2AKDM4EMAPTCNR2 | |
| SCHEMBL13011241 | 0.73 | PTGER4 (0.57) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL13011164 | 0.72 | PTGER4 (0.52) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL13011269 | 0.69 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EPARP1PSEN1 | |
| SCHEMBL13011140 | 0.69 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL13011141 | 0.68 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EPARP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119704-A1 | ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |