Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12416078 | 0.95 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9610668 | 0.88 | THRB (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13486939 | 0.85 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14330801 | 0.85 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28866183 | 0.85 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12199990 | 0.83 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28255778 | 0.83 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5233396 | 0.83 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL25211836 | 0.83 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9303527 | 0.83 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304178-B2 | Top antireflective coating composition containing hydrophobic and acidic groups | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-11-06 | — | — | US | disclosed |