Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.66 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635186 | 0.89 | MAPK14 (0.78) | MAPK14 | |
| SCHEMBL4382379 | 0.89 | MAPK14 (0.82) | MAPK14 | |
| SCHEMBL13635874 | 0.87 | MAPK14 (0.63) | MAPK14 | |
| SCHEMBL4392919 | 0.82 | MAPK14 (0.89) | MAPK14 | |
| SCHEMBL4379163 | 0.79 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL4386801 | 0.79 | MAPK14 (0.78) | MAPK14 | |
| SCHEMBL4478817 | 0.79 | MAPK14 (0.82) | MAPK14 | |
| SCHEMBL4467417 | 0.78 | MAPK14 (0.89) | MAPK14 | |
| SCHEMBL4485643 | 0.77 | MAPK14 (0.73) | MAPK14 | |
| SCHEMBL4471003 | 0.77 | MAPK14 (0.78) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-B1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORP (US) | 2009-11-18 | — | — | EP | disclosed |