Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365106 | 0.93 | HSD11B1 (0.73) | HSD11B1CYP3A4 | |
| SCHEMBL14606976 | 0.86 | HSD11B1 (0.64) | HSD11B1CYP3A4 | |
| SCHEMBL13636406 | 0.85 | HSD11B1 (0.71) | HSD11B1CYP3A4 | |
| SCHEMBL4665248 | 0.84 | HSD11B1 (0.80) | HSD11B1CYP3A4 | |
| SCHEMBL4364570 | 0.84 | HSD11B1 (0.80) | HSD11B1CYP3A4 | |
| SCHEMBL4664014 | 0.81 | HSD11B1 (1.00) | HSD11B1CYP3A4 | |
| SCHEMBL4367317 | 0.81 | HSD11B1 (1.00) | HSD11B1CYP3A4 | |
| SCHEMBL4371737 | 0.79 | HSD11B1 (0.73) | HSD11B1CYP3A4 | |
| SCHEMBL4367319 | 0.78 | HSD11B1 (0.73) | HSD11B1CYP3A4 | |
| SCHEMBL4365119 | 0.78 | HSD11B1 (0.73) | HSD11B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622492-B2 | Pyrazolones as inhibitors of 11β-hydroxysteroid dehydrogenase | HOFFMANN-LA ROCHE INC. (US) | 2009-11-24 | — | — | US | disclosed |